Breaking Convention Series: Dr. Torsten Passie – The Science of Microdosing Psychedelics

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In this episode, Kyle sits down with Dr. Torsten Passie, Professor of Psychiatry and Psychotherapy with the Hanover Medical School in Germany. In the show, they cover a range of topics on Dr. Passie’s studies on microdosing.

3 Key Points: Psychedelic research in the University setting died off after 2004, but is finally seeing an increase as the psychedelic revolution continues to grow. There is very little to no documentation of doctors doing self-experimenting with psychedelic drugs. It’s becoming popular for therapists to use the substances used on their patients, more common to do the self-work before doing the work on others. Even if microdosing does not produce any significant effects and it is all placebo, the trend is a new way to introduce it into our society.

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Show Notes About Dr. Passie Dr. Passie has been researching psychedelics for 25 years He specializes in the therapeutic use of psychedelic drugs He has found difficulties in researching psychedelics during prohibition Dr. Passie had a mystical experience before using psychedelics and then became interested in psychedelic use He had grown up as an atheist, a materialist, and his experience required him to change his psychological state His perception of reality was irritated and he had to see a therapist to integrate this experience He said that this was frustrating because he was young and still in search for his identity Through all of this, he decided to study medicine and become a psychedelic doctor He became very conscious that he was on the right track Research Studies The researchers were the only ones doing studies on psychedelic states, there wasn’t much happening at the Universities He did studies with cannabis, ketamine and even laughing gas The research then was on how cannabinoids can help with psychosis They were not successful with that, but it came to be that CBD was a neuroleptic and an anti-psychotic Research pretty much stopped after 2004 due to new laws and the cost of the research Dr. Passie does mention that in the past 10 years research has really taken off again and that we are really seeing the renaissance of psychedelic culture In most of the literature of doctors doing self-experimenting, there is very little to no documentation of doctors doing self-experimenting with psychedelic drugs Kyle mentions that MAPS has included into their training protocol to allow for therapists to have self-experiments with the substances that they are using on patients Kyle also mentions he can’t imagine trying to hold space in breathwork without having had his own experiences with breathwork Dr. Passie says that the history of self-experimentation with psychedelics has shown that the participants can become ‘gurus’ and lose their objectivity, he uses Timothy Leary as an example But with only a few times of self-experimentation, maybe 2-4 times, he doesn’t see risks HPPD Hallucinogen persisting perception disorder (HPPD) is a disorder in which a person has flashbacks of visual hallucinations or distortions experienced during a previous hallucinogenic drug experience Dr. Passie thinks there is a selection bias in what is published about HPPD Its more common to have a study published that talks about an adverse effect of LSD than a benefit of it Hundreds of thousands of studies were conducted in the 50’s, and no one claimed that this phenomenon came up And now one person has conducted a study, claiming that this phenomena exists Dr. Passie says that this pattern happens among people who are prone to anxiety and who are dissociative He says that most subjects that claim to experience HPPD, have experienced visuals even before ever taking LSD Microdosing It has been known to not have any effects from 15-20 micrograms of LSD 20-50 micrograms of LSD is considered mini-dosing, where you can feel some type of effects from it, but not as much as the full dose Dr. Passie says it is strange for people to claim to have increased cognition during microdosing based on conventional data that shows that LSD produces poor cognitive function He thinks that whatever the effects are of LSD at a high dose, that the effects at a low dose are the same, just less, not completely different effects He believes that there is some placebo effect with microdosing In terms of the microdosing trend, Dr. Passie is critical about the productivity factor, he does believe in the creativity factor though The flow state may also be increased with microdosing He claims that in his own experience with microdosing, he doesn’t experience the flow state, in fact he experiences a feeling of agitation …

Comments

@Fawkinchit says:

I'm shocked that Dr. Torsten Passie is questioning the reality of HPPD, how much longer until he is recommending lobotomies? There are TONS of studies on hallucinogens with people coming back with reports of long term permanent adverse affects, some involved in the studies were even reported to commit suicide because of their complaints. Rare occurrences of a condition does not suggest improbability of the condition. Dr. Torsten Passie is also basically arguing that these are reported due to biasedness on part of the physicians which is not a critical or definitive observational argument, which immediately invalidates his position. Also Dr. Passie is probably just trying to protect research funding. Plain and simple. I get that they need funding but why corrupt the innocent for it.

@benlewis9228 says:

case reports "Fake" ?? hppd is a real condition. there is a massive suffering patient population of thousand of sufferers crying out for help and it is only growing. I myself have been enduring chronic hppd for over 29 years. Yes Dr Abraham is the leading researcher and has documented thousands of cases also. Anxiety and dissociation and depersonalisation are symptoms of hppd only. None of us had any visual disturbances before taking hallucinogens. The cause was LSD. Sorry but this is completely false. You cannot just ignore this real condition by trying to sweep it under the rug in the interest of making $$. 1 out of 100,000 completely FALSE. HPPD can be there in clinical settings as there are many documented cases even from micro-dosing. so sad.. You only have to join our support group for proof on 10s of thousands of hppd suffers https://www.facebook.com/groups/HPPDSC some of them only 20 years old who contracted it from one tab of acid only.

@wokeman9928 says:

Intro music name ?

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