How one psychedelic trip can alter an entire lifetime | Matthew Johnson: Full Interview
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“Psychedelics crosscut so many interesting domains. They've been used for time immemorial by indigenous cultures. In our own Western cultural history, they really exploded on the scene in the 1960s, and were associated with radical changes to society.”
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Up next, Are drugs really frying your brain? | Dr. Carl Hart ► https://www.youtube.com/watch?v=90MHZbXrmY0
Psychedelic research is enjoying a renaissance. Matt Johnson, a professor of psychiatry and behavioral sciences at Johns Hopkins, is at the forefront of the movement to redefine our understanding of the mind and its interaction with these powerful substances.
As psychedelic compounds steadily enter the sphere of clinical trials, Johnson's groundbreaking research underscores their potential to bring about a paradigm shift in psychiatry, neuroscience, and pharmacology.
0:00 Meet Dr. Matthew Johnson
0:25 Why are psychedelics unique among drugs?
3:42 What does the term ‘psychedelic’ mean?
7:40 What is hallucinogen vs. entheogen vs. psychedelic?
13:46 The first wave: Hofmann, Leary, and the CIA
18:54 Are psychedelics legal?
21:39 What are the main effects of psychedelics?
24:28 How do psychedelics work in the brain?
39:57 Are psychedelics dangerous? What is the link to schizophrenia?
48:43 What are the biggest risks of psychedelics?
50:42 How do “all arounders” get to the core of psychiatric disorders?
54:48 What is the role of a guide in a psychedelic session?
58:22 What is the focus and impact of your research?
1:03:44 What really amazes you in your research?
1:09:54 Why are we in a psychedelic renaissance?
1:17:09 What are some pitfalls of psychedelic medicine?
Read the video transcript ► https://bigthink.com/series/full-interview/psychedelic-drugs-101/?utm_source=youtube&utm_medium=video&utm_campaign=youtube_description
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About Matthew Johnson:
Matthew W. Johnson, Ph.D., is The Susan Hill Ward Endowed Professor of Psychedelics and Consciousness Research at Johns Hopkins. Working with psychedelics since 2004, he is one of the world’s most widely published experts on psychedelics. He has published research on psychedelics and mystical experience, personality change, tobacco smoking cessation, cancer distress treatment, and depression treatment. In 2021 he received as principal investigator the first grant in 50 years from the US government for a treatment study with a classic psychedelic, specifically psilocybin in treatment of tobacco addiction. He is also known for his expertise in behavioral economics, addiction, sexual risk behavior, and research with a wide variety of drug classes. He’s been Interviewed by Anderson Cooper on 60 Minutes, the New York Times, the Washington Post, the Wall Street Journal, CNN, NPR, Fox News, Fox Business News, BBC and in Michael Pollan’s book How to Change Your Mind.
Become a Big Think member to unlock expert classes, premium print issues, exclusive events and more: https://bigthink.com/membership/?utm_source=youtube&utm_medium=social&utm_campaign=yt_desc
“Psychedelics crosscut so many interesting domains. They’ve been used for time immemorial by indigenous cultures. In our own Western cultural history, they really exploded on the scene in the 1960s, and were associated with radical changes to society.”
Subscribe to Big Think on YouTube ► https://www.youtube.com/channel/UCvQECJukTDE2i6aCoMnS-Vg?sub_confirmation=1
Up next, Are drugs really frying your brain? | Dr. Carl Hart ► https://www.youtube.com/watch?v=90MHZbXrmY0
Psychedelic research is enjoying a renaissance. Matt Johnson, a professor of psychiatry and behavioral sciences at Johns Hopkins, is at the forefront of the movement to redefine our understanding of the mind and its interaction with these powerful substances.
As psychedelic compounds steadily enter the sphere of clinical trials, Johnson’s groundbreaking research underscores their potential to bring about a paradigm shift in psychiatry, neuroscience, and pharmacology.
0:00 Meet Dr. Matthew Johnson
0:25 Why are psychedelics unique among drugs?
3:42 What does the term ‘psychedelic’ mean?
7:40 What is hallucinogen vs. entheogen vs. psychedelic?
13:46 The first wave: Hofmann, Leary, and the CIA
18:54 Are psychedelics legal?
21:39 What are the main effects of psychedelics?
24:28 How do psychedelics work in the brain?
39:57 Are psychedelics dangerous? What is the link to schizophrenia?
48:43 What are the biggest risks of psychedelics?
50:42 How do “all arounders” get to the core of psychiatric disorders?
54:48 What is the role of a guide in a psychedelic session?
58:22 What is the focus and impact of your research?
1:03:44 What really amazes you in your research?
1:09:54 Why are we in a psychedelic renaissance?
1:17:09 What are some pitfalls of psychedelic medicine?
Read the video transcript ► https://bigthink.com/series/full-interview/psychedelic-drugs-101/?utm_source=youtube&utm_medium=video&utm_campaign=youtube_description
© Freethink Media Inc., All Rights Reserved.
———————————————————————————-
Go Deeper with Big Think:
►Become a Big Think Youtube Member
Get exclusive classes and early, ad-free access to new releases without leaving Youtube. https://www.youtube.com/@bigthink/membership/
►Become a Big Think Web Member
Get the entire Big Think Class library, premium print issues, live events, and more.
https://bigthink.com/membership/
►Subscribe to Big Think on Substack
Get all of your favorite Big Think content delivered to your inbox.
https://bigthinkmedia.substack.com/subscribe/
———————————————————————————-
About Matthew Johnson:
Matthew W. Johnson, Ph.D., is The Susan Hill Ward Endowed Professor of Psychedelics and Consciousness Research at Johns Hopkins. Working with psychedelics since 2004, he is one of the world’s most widely published experts on psychedelics. He has published research on psychedelics and mystical experience, personality change, tobacco smoking cessation, cancer distress treatment, and depression treatment. In 2021 he received as principal investigator the first grant in 50 years from the US government for a treatment study with a classic psychedelic, specifically psilocybin in treatment of tobacco addiction. He is also known for his expertise in behavioral economics, addiction, sexual risk behavior, and research with a wide variety of drug classes. He’s been Interviewed by Anderson Cooper on 60 Minutes, the New York Times, the Washington Post, the Wall Street Journal, CNN, NPR, Fox News, Fox Business News, BBC and in Michael Pollan’s book How to Change Your Mind.
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Sounds good. It could work wonders, with the right therapist/clinician. At least with mushrooms, Because we treated them as crime for so long, we’ve created more need for therapy than ever, that much is for sure.
There is so much hype around psychedelics, and some of it is actually true. But one has to realize it's in vogue, and has been for some time, to talk about how psychedelics radically changed one's life for the better.
Prince Harry took ayahuasca, was enlightened by it, and then went on to slander his family for a 100 million dollar payout. Brian Rose of London Reel fame took ayahuasca and overcame his addiction to alcohol, and then went on to raise funds for his supposed battle for free speech and subsequently pocketed the money. Jada Pinkett Smith seemed to think disclosing her ayahuasca healing would cast her in a new and hip light, absolving her of her traumas and tarnish -this is the most common refrain we hear. Alan Watts, early promoter of psychedelics went on to drink himself to death. Timothy Leary was a morphine addict in the latter half of his life. Terence McKenna eventually scared himself away from psychedelics. And then there's Sid Barrett, Vince Taylor, Brian Wilson, Peter Green, etc. Moby dropped acid as a young man and suffered anxiety from that point onward. So can a single dose of psychedelics change one's life in ineffable ways? You betchya.
1:37:59 The Therapy Session
1:34:23 The Heroic Dose
1:33:03 Psilocybin, the wonder drug. Here you go, you prejudiced self-righteous all-perfect close-minded bigot.
1:13:53 The Paradigm Shift: The old guard has to die out first before the renaissance of the new idea/new theory.
1:03:55 Take note!
1:00:40 Important
45:34 Ira Levin's "Rosemary's Baby".
I hallucinated a fly around him the whole time.
Cautionary tale folks..if you feel like your last trip broke your brain don’t do it again. If you suddenly switch your self identity from I to we for a year when talking about your individual self do not take more acid. If you get psychosis and see a man in the corner of your eye even when not tripping don’t do it again. I thankfully didn’t do it again but my brain for many years has felt it’s on an edge an edge it can fall off at any point.
PCP and Ketamine are Dissociatives (Dissociative Anesthetics)
Walls breathing is You rocking while breathing and not compensating visually (filter off)
Colors can be overwhelming because it is Your WHOLE FIELD UPDATING as oipposed to small changes only. it is Visual feature Hasllucination.
Is Psychedelic Therapy looking to DEBILITATE or ENABLE patient? Biopolitically speaking. GIVE THEM COCAINE !!!
It is Psychiatry – Psychopaths slip drugs to future Schizophrenia patients
MEDICAL to DEBILITATE or MEDICAL to HEAL? – in psychiatry Psychopaths aim to commit people for medicine to DEBILITATE them.
I overdosed on 10g shrooms – 8B GEOMETRY Level hallucinations 8B – Perceived exposure to inner mechanics of consciousness – FULL OVERRIDE – REAL STUFF WAS DISSAPEARING and NOT FAKE STUFF OVERLAY !!! 5-meo-dmt u think ur about to die of sensory overload // MDPM – Methylene Dioxy Phentermine is between MDMA and LSD
Kappa opioid blockage PREVENTS ADDICTION/Dysphoria – I can take a Stimulant and Not Redose! with 10mg Aticaprant – Naltrexone is similar
Voacangine Replaced Ibogaine – small doses are stimulant other than that may be Deliriant?? Anticholinergic??
I ate 30tabs LDS in a month – to quench Cocaine Addiction – With Cocaine EVERY PLACEBO IS ADDICTIVE
I took 10g shrooms, forgot about it, went to run errands a nd Baam – overdose! DMT demons were charging past me with flashlights! and a zinging sound.
It was the PSYCHOPATHS! I have Schizophrenia – Only NON-DECOY – Try me ! the REAL DEAL.
YEs- COWORKERS PULLED a 4-AcO-MET Psychedelic WiFi 5G Telepathy invaded TRIP with my soon to be Wife and First Love – I thought She was The room I was Inside 😀
7mg Adrenochrome Research – Me myself and I in my R&D Company
Nicotine / Cotinine an Antipsychotic – Quit nicotiune u bout to have a psychosis = MORE CRAP
AND Research Chemical Cathinones replacement for Cocaine addiction == PREMANENT PSYCHOSIS HoooRay!!!
HARD PROBLEM SOLUTION = repetitive Correlatrion of Patterns and Others apopearing to be Conscious = Most Energy Efficient – Makes You conscious too Alhough You Just a Ball+stick ATOM MODEL 😉
OTHER WAY AROUND THEY APEAR CONSCCIOUS AND YOU ASUME YOU ARE – NOONE IS. – It is A duality.
WAHAT is THE EVIDENCE You Like Icecream? Easting it is NOT – IT MAY BE BY FORCE
TAK-653 has same AD effects as Ketamine Without Hallucination and Psychotsis – AMPA – they traced the brain circuit Further Diown
Psylocibin Biweekly use MAX due to Tolerance
DOES IT INCLUDE 5G XR Synthetic Telepathy AND Where are the Psychos doing it? – IT MAY FOR ALL YOU KNOW or are You in on it?
10:38 The scientist doesn't like the word "hallucinogen" yet cannot stop reductively calling these ancient medicines "drugs." This is on some level a pharma strategy to "discover" a continent of wonder and healing that humanity was already an heir to. Ah progress!
Chaperone is a good term…
It's like trying to convey to someone how real a vivid dream was. To you, if was so real and to them, it was nothing.
The first time I do anything it radically changes my life
Damn reading these comments I wish I could give u good trusted acid. I know people think I’m crazy, but I know people living in the Midwest to the cities can all benefit
I love hearing people’s psychedelic trips it’s one of my favorite storytelling . I have also wondered for many many years if it is possible to change everything with one trip, I know there’s wonky acid and dmt and Changa etc but I think I had some fairly life changing clean love like acid from sf when I was I college and yeah it’s never been the same
Wow, I just discovered that I'm sitting at the exact center of the visible universe. Another gummie is in order.