Here's Why You Want To Know About Mushrooms and Depression

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Psilocybin is a compound found in mushrooms that has psychedelic properties. Psychedelic means it makes you hallucinate. Psilocybin works in the brain by activating the 5-HT2A receptor on the neuron to increase serotonin.

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Psilocybin has been used recreationally for years and is known to broaden your thinking, relax you and amplify your emotions.

There have been studies that have shown that after only two doses of psilocybin, the person was more mentally flexible and less uptight about things. These attitude changes 7-12 months after the 1-2 doses.

There’s a real race to get this to market. The FDA granted breakthrough therapy designation in 2018 to Compass Pathways for treatment resistant depression using a range of doses. Then in November 2019, the FDA granted the designation to the company Usona Institute to treat regular depression (not treatment resistant) using a single dose.

Depression inside of bipolar disorder is different from unipolar depression. Psilocybin is being studied for the treatment of unipolar depression. We don’t know what affect it will have on possibly triggering mania or psychosis. This doesn’t mean that it can’t help with the depression that comes with bipolar disorder, though. We’ll first have to see what side effects are associated with the drug once they have completed the trials to anticipate how it may affect bipolar disorder.

References
Erritzoe D, Roseman L, Nour MM, et al. Effects of psilocybin therapy on personality structure. Acta Psychiatr Scand. 2018;138(5):368–378.

Lyons T, Carhart-Harris RL. Increased nature relatedness and decreased authoritarian political views after psilocybin for treatment-resistant depression. J Psychopharmacol. 2018;32(7):811–819.

Interested in the clinical trials?
Usona Institute for major depression
https://usonaclinicaltrials.org/major-depressive-disorder-psilocybin-clinical-trial-psil201

Compass Pathways for treatment resistant depression
https://compasspathways.com/research-clinical-trials/

Want to know more about mental health and self-improvement? On this channel I discuss topics such as bipolar disorder, major depression, anxiety disorders, attention deficit disorder (ADHD), relationships and personal development/self-improvement. I upload weekly. If you don’t want to miss a video, click here to subscribe. https://goo.gl/DFfT33

Disclaimer: All of the information on this channel is for educational purposes and not intended to be specific/personal medical advice from me to you. Watching the videos or getting answers to comments/question, does not establish a doctor-patient relationship. If you have your own doctor, perhaps these videos can help prepare you for your discussion with your doctor.

Comments

@ronaldrothchild4068 says:

JFK, PRIOR TO THE PRESIDENCY WAS IN THE UNITED STATES HOUSE OF REPRESENTATIVES AND THEN ADVANCED TO THE UNITED STATES SENATE, SO THEIR-FORTH HE REPRESENTED MASSACHUSETTS IN BITH HOUSWS OF THE UNUTED STATES CONGRESS, DID LSD BUT BANNED IT?

@infra703 says:

Great Job ❤️

@hamishmounsey3989 says:

When will this be widely available I wonder

@Scott_French_Musics says:

My whole life I believed these were dangerous. What a waste of half my life. One trip is like years of therapy. Unlearn everything.

@jeroona5648 says:

Scheduling systems are so stupid. If the government would actually listen to their own guidelines alcohol would be schedule 1 in place of shrooms

@mohammedfazalkhan7310 says:

Does Psilocybin can cure bipolar disorder

@OfficialBukason says:

I strongly recommend you try shrooms its a psychedelic treatment for depression when taken with a guide, saved me from years of depression and anxiety when I lost my family in car accident, I'll refer long term mycologist

@ingridsara213 says:

I have been depressed for a long time, but after taking shrooms few months ago, l feel much happier and highly motivated and my ADHD gone , lost a ton of anxiousness and had a few epiphanies about how I should live my life. I decided to buy an ounce for backup, but haven’t yet felt the need to take any more since then.

@AB608052 says:

I never had a dad.. to you know, say, you're with some girl, what you got to do, you whip it out, you say what are we going to do about this? That's what it's about. It's a murky problem. It's a lot of things.. but for starters, I went to see a psychiatrist and I expected help and what the fuck did they do. Instead, can they reason through this. I can't believe all this, and there's no reward.

Two different treatments for depression. They sort of do almost the exact opposite thing.. One is paring down their neurosis, the other is increasing their flexibility. But still. it could be simple. Oh the problem was depression. But then still.. Oh different TYPES of depression.. Well the doctor is going to help you sort that out, that's what they do. Don't tell me STILL no. Not even a fruit cup? So what's the truth about psychiatry? Can you.. or you and the dr. pare down this problem so that it's just you. That would be the limit on how well you can do. And then understanding that, there might be another level down, you could do more for yourself than you realize. So what kind of psychiatrist are you seeing, this could never end.

But the job pays money, so at some point, the doctor probably ought to say, this tractor can't pull another foot.. but

@AllThingsFitnessandLifestyle says:

Does it help heal trust issues

@chadhoover9702 says:

Going down the schedules gets dangerous. The higher scheduled substances are the most destructive‼️

@anthonycastro2146 says:

Psychiatrists are now treating psychosis and inducing psychosis Anyway to make a buck.

@SanFranMission415 says:

So are you saying if I start to take mushrooms, I will become a liberal who uses pronouns and want to drive a Tesla?

@jakegenocide says:

I have treatment resistant MDD and Delusional Disorder, psilocybin helps me spot what is real and what is a delusion. It also helps me feel whole again.

@spiet7380 says:

Did you know that Ronald Reagan banned hallucinogens and drugs because acid and shrooms had military aged men declining to fight in Vietnam? The Government doesn't do anything for "your good" It protected itself and it's war machine.

@GregoryScroggins says:

Where do u get the Psilocybin ?

@bdee1084 says:

I’ve got a slight allergy to mushrooms and wonder if I could still use them medicinally

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